Other two-week shapes. Rome (4 nights), Tuscany (4) and the Amalfi Coast (5) for a slower trip without Venice; or Rome and Florence for a week, then Sicily for the second, flying from Rome to Palermo or Catania.
How we move you between bases. Typical times on the fastest trains in 2026: Venice to Florence about 2 h 15, Florence to Rome about 1 h 30, Rome to Naples about 1 h 10, Naples to Salerno about 35 minutes, Rome to Milan about 3 h. Regional trains serve the Cinque Terre and the lakes. We reserve high-speed seats together, send luggage-friendly transfers where the trains stop short, and use drivers on the Amalfi Coast and in the mountains. See Italy by train and Milan to Venice by train.
Budget in 2026. At the daily rates our trip cost calculator uses for Italy, two weeks costs about €3,050 to €4,150 (about $3,480 to $4,730) per person in comfortable 4-star hotels, €5,000 to €6,800 (about $5,700 to $7,750) in boutique 4-star and 5-star hotels with private guides, and €9,000 to €12,200 in luxury hotels, two people sharing, with first-class trains, meals and guided visits, before flights. Routes with Switzerland or summer nights on Lake Como and the Amalfi Coast sit at the top of each range. Our Italy cost guide details each line.
Best season. May, June and September suit the grand tour: the sea is warm, hotels on the coast are open and the cities are not yet at their hottest. Route 2 needs the summer lift season, roughly mid-June to mid-September, and Route 3 is at its best from June to September. Day visitors to Venice paid an access fee on 60 days between April 3 and July 26, 2026; overnight guests, which covers every route here, are exempt. Our best time to visit Italy guide compares the months.
Accessibility. For wheelchair users, we replace the Cinque Terre and the Amalfi villages, which are built on steps, with Lake Garda and Sorrento, and keep Venice, Florence and Rome with step-free hotels, adapted transfers and Sala Blu assistance for every train. See our wheelchair-accessible Italy guide and accessible trips.
Shorter on time? See Italy in 10 days or Italy in 7 days, and our Italy travel guide for every region. When your dates are set, ask for your two weeks, priced within 48 hours.